Publications by authors named "A Lomax"
Campi Flegrei is a densely populated volcanic area in Italy. Its inner caldera periodically experiences uplift and subsidence, known as bradyseism, also accompanied by seismic activity. In the last decade, with uplift rates up to 2 cm/month, about nine-thousand earthquakes were recorded.
View Article and Find Full Text PDF. Image-guided and adaptive proton therapy rely on daily CBCT or CT imaging, which increases radiation dose and radiation-induced cancer risk. Online adaptation however also reduces setup uncertainty, and the additional risk might be compensated by reducing the setup robustness margin.
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- This study examines the tolerance development to opioids, focusing on fentanyl and a new μ-opioid receptor agonist, NFEPP, which is activated in acidic environments typical of inflammation.
- Researchers conducted tests on mice with colitis to assess the analgesic effects and tolerance of both opioids over five days.
- Results showed that while fentanyl led to tolerance and cross-tolerance, NFEPP did not, suggesting it could offer pain relief without the risk of escalating dosages and increased side effects.
Article Synopsis
- The study evaluated craniospinal irradiation (CSI) treatments using protons at the Paul Scherrer Institute, focusing on local recurrences and late toxicity outcomes for 71 patients, mostly children and young adults with tumors like medulloblastoma and ependymoma.
- Data from patients treated in both prone and supine positions were analyzed, revealing that supine positioning led to lower systematic and random errors in treatment setup, resulting in more accurate dosing.
- The research concluded that local failures in treatment were not linked to inaccuracies in radiation dosing, and there was no observed correlation between treatment-related toxicities and increased radiation effects.