Facing SARS-CoV-2 emergence on the animal health perspective: The role of the World Organisation for Animal Health in preparedness and official reporting of disease occurrence.

Aims: Current data suggest that SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) emerged from an animal source. However, to date, there is insufficient scientific evidence to identify the source of SARS-CoV-2 or to explain the original route of transmission to humans. A wide range of mammalian species have been shown to be susceptible to the virus through experimental infection, and in natural environments when in contact with infected humans.

Influence of substrate temperature on the properties of ZnTe:Cu films prepared by a magnetron co-sputtering method.

Copper-doped Zinc Tellurium (ZnTe:Cu) films were deposited on borosilicate glass using magnetron co-sputtering technique. The influence of the substrate temperature on the structural, morphological, optical and electrical properties of ZnTe:Cu films was investigated by X-ray diffraction (XRD), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), UV-Vis spectrophotometer and Hall effect measurement system. The results indicate that substrate temperature significantly affects the properties of the ZnTe:Cu films.

Antigenotoxic and anticytotoxic effect of camel milk in mice treated with cisplatin.

Camel milk (CM) has good nutritive value, in addition to its antigenotoxic and anticytotoxic effects. Therefore the aim of this investigation was to evaluate the capacity of CM to inhibit the micronucleated polychromatic erythrocytes (MnPCEs) in the bone marrow and improve the mitotic activity produced by cisplatin. Cisplatin is one of the most widely used antineoplastic drugs in the treatment of cancer.

Sufentanil with and without diazepam for coronary artery bypass graft surgery.

We studied the sufentanil-sparing effect of diazepam for anesthesia induction and compared stress responses (hemodynamics, plasma catecholamine levels) and sufentanil and diazepam plasma levels during sufentanil anesthesia with or without diazepam. Sixteen aortocoronary bypass surgery patients were randomly assigned to receive diazepam (D) 100 micrograms/kg (Group DS) or not (Group S), then sufentanil (Sf) infused at 150 micrograms/min until unconsciousness (U). After tracheal intubation, the Sf dose for U (Sfu) was repeated, preceded in Group DS by D 150 micrograms/kg.

Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis.

T-cell receptor (TCR)-mediated apoptosis in immature thymocytes and T-cell hybridomas is calcium dependent and can be inhibited by cyclosporin A (CsA). Induction of the orphan steroid receptor Nur77 (NGFI-B) is required for activation-induced apoptosis. Here, we examined the regulation of Nur77 expression, in response to apoptotic TCR signals, which consists of kinase C and calcium pathways.