Publications by authors named "A Lien"
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is governed by sets of co-regulated and physically clustered genes known as biosynthetic gene clusters (BGCs). To share information about BGCs in a standardized and machine-readable way, the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard and repository was initiated in 2015.
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- Hepatitis is a significant global health concern, prompting early screening recommendations, especially for those without symptoms.* -
- A study with nearly 58,000 participants in Taiwan investigated how lifestyle and liver function biomarkers influenced the adoption of a new cancer screening program, finding a connection to faster acceptance among healthier individuals.* -
- Understanding these factors can help healthcare providers enhance screening strategies for individuals at risk of hepatitis and liver cancer, potentially lowering mortality rates.*
Motivation: INCA is a powerful tool for metabolic flux analysis, however, import and export of data and results can be tedious and limit the use of INCA in automated workflows.
Results: The INCAWrapper enables the use of INCA purely through Python, which allows the use of INCA in common data science workflows.
Availability And Implementation: The INCAWrapper is implemented in Python and can be found at https://github.
Ancient DNA is highly degraded, resulting in very short sequences. Reads generated with modern high-throughput sequencing machines are generally longer than ancient DNA molecules, therefore the reads often contain some portion of the sequencing adaptors. It is crucial to remove those adaptors, as they can interfere with downstream analysis.
View Article and Find Full Text PDFWidespread support for a global species list with a formal governance system.
Proc Natl Acad Sci U S A
November 2023
Taxonomic data are a scientific common. Unlike nomenclature, which has strong governance institutions, there are currently no generally accepted governance institutions for the compilation of taxonomic data into an accepted global list. This gap results in challenges for conservation, ecological research, policymaking, international trade, and other areas of scientific and societal importance.
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