Publications by authors named "A Lhomme"
Article Synopsis
- - The study focuses on how gene expression patterns arise from interactions within gene networks, aiming to develop a system that reveals both short- and long-range spatial correlations among genes.
- - Researchers utilized synthetic biology, statistical models, and computational simulations to analyze synthetic gene networks in E. coli, observing that these networks can self-organize into complex spatial patterns that mimic behaviors found in physical systems like magnets.
- - The results enhance our understanding of spatial relationships in gene networks within growing cell populations, potentially aiding future research and engineering of gene patterns in both bacterial and eukaryotic systems.
Oral rehabilitation of patients presenting multiple microdontia is a real therapeutic challenge. These alterations in size, often associated with other dental anomalies, have aesthetic and functional repercussions for patients and can lead to significant psycho-social consequences. We report here the case of an 11-year-old patient with bilateral sectorial microdontia and agenesis of teeth numbers 13 and 23.
View Article and Find Full Text PDFIn intrapulmonary arteries (IPA), endothelial cells (EC) respond to mechanical stimuli by releasing vasoactive factors to set the vascular tone. Piezo1, a stretch-activated, calcium-permeable channel, is a sensor of mechanical stress in EC. The present study was undertaken to investigate the implication of Piezo1 in the endothelium-dependent regulation of IPA tone and potential involvement of Piezo1 in pulmonary hypertension, the main disease of this circulation.
View Article and Find Full Text PDFBackground: Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored.
Results: In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes.