Publications by authors named "A Lesca"
Introduction: Anorectal melanoma (ARM) is rare and highly lethal neoplasm. It has a poorer prognosis compared with cutaneous ones. Sentinel lymph node biopsy (SLNB) has become the preferred method of nodal staging method for cutaneous melanoma.
View Article and Find Full Text PDF[18F]DOPA PET for lesion definition and contouring using different thresholds in patients with gliomas.
Q J Nucl Med Mol Imaging
September 2024
Article Synopsis
- The study examines the effectiveness of ESTRO-EANO guidelines for RT-planning in glioblastomas using [F]DOPA-PET, comparing their target definition thresholds (1.6-1.8) with traditional biological-tumor-volume (BTV) thresholds derived from the striatum. !* -
- An analysis of 50 glioma patients found that the striatum SUV
max threshold often resulted in smaller and less accurate tumor volumes, with significant discrepancies noted in many cases. !* - - The research concludes that the ESTRO-EANO thresholds for defining tumor volume are compatible with [F]DOPA-PET scans, while using the striatal SUV
Background: Spinocerebellar ataxia 17 (SCA17) is a rare autosomal dominant form of inherited ataxia, caused by heterozygous trinucleotide repeat expansions encoding glutamine in the TATA box-binding protein (TBP) gene.
Case Description: We describe the clinical history, neuropsychological, and neuroimaging findings of a 42-year-old patient who presented for medical attention showing prevalent behavioral and cognitive problems along with progressively worsening gait disturbances. The patient's family history indicated the presence of SCA17 in the maternal lineage.
Purpose: This study evaluated the characteristics of patients with head and neck (H&N) melanoma who underwent sentinel lymph node biopsy (SNLB) and assessed the clinical course of patients categorizing subjects according to SLNB status and melanoma location (scalp area vs. non-scalp areas). Methods: Patients undergoing SLNB for melanoma of H&N from 2015 to 2021 were prospectively characterized according to sentinel lymph node (SLN) status.
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