Publications by authors named "A Lepoutre"
Cyanobacteria are a potential threat to aquatic ecosystems and human health because of their ability to produce cyanotoxins, such as microcystins (MCs). MCs are regularly monitored in fresh waters, but rarely in estuarine and marine waters despite the possibility of their downstream export. Over a period of two years, we monthly analyzed intracellular (in phytoplankton) and extracellular (dissolved in water) MCs at five stations along a river continuum from a freshwater reservoir with ongoing cyanobacterial blooms to the coast of Brittany, France.
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- COVID-19 surveillance began in the WHO European Region on January 27, 2020, with the first European cases reported shortly after.
- By February 21, nine European countries had reported 47 cases, many linked to clusters in Germany and France, while others were infected in China.
- As of March 5, the total number of COVID-19 cases in the region surged to 4,250, highlighting the impact of delayed isolation efforts.
The environmental neurotoxin β-methylamino-l-alanine (BMAA) may represent a risk for human health. BMAA accumulates in freshwater and marine organisms consumed by humans. However, few data are available about the kinetics of BMAA accumulation and detoxification in exposed organisms, as well as the organ distribution and the fractions in which BMAA is present in tissues (free, soluble bound or precipitated bound cellular fractions).
View Article and Find Full Text PDFThe environmental neurotoxin β-methylamino-L-alanine (BMAA) may represent a risk for human health in case of chronic exposure or after short-term exposure during embryo development. BMAA accumulates in freshwater and marine organisms consumed by humans. It is produced by marine and freshwater phytoplankton species, but the range of producers remains unknown.
View Article and Find Full Text PDFBackground: In France, pneumococcal vaccination in adults is recommended for risk groups (chronic conditions/immunosuppression). We conducted a study on invasive pneumococcal disease (IPD) in adults to identify factors associated with disease severity and death.
Methods: We included IPD cases, excluding meningitis, from 25 acute care hospitals in 6 regions.