Publications by authors named "A Leon Coria"

Objective: To evaluate the effectiveness of social resource referrals after social needs screening among caregivers of pediatric inpatients by assessing (1) the rates of resource connection, (2) caregiver perception of resource helpfulness, (3) barriers to connection, and (4) resolution of needs.

Methods: We conducted a cross-sectional survey of families discharged from our pediatric inpatient floor between October 2021 and June 2022 who had screened positive for unmet social needs and received a referral to at least 1 community resource during their hospitalization. We surveyed caregivers by telephone 1 month to 1 year post-intervention, inquiring about their perception of and experience with referrals.

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Article Synopsis
  • The study explores the process of 18S nonfunctional rRNA decay (NRD), which is crucial for maintaining ribosome quality by removing nonfunctional rRNA in mammals.
  • It reveals that NRD operates through the integrated stress response (ISR) involving GCN2 and RNF10-mediated ubiquitination of ribosomal proteins, linking stress responses to ribosome function.
  • The research shows that nonfunctional 18S rRNA can cause translational arrest, and the ISR works to prevent translation initiation failures, highlighting a feedback system that monitors ribosome functionality during protein synthesis.
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Co-infections are a common reality but understanding how the immune system responds in this context is complex and can be unpredictable. Heligmosomoides bakeri (parasitic roundworm, previously Heligmosomoides polygyrus) and Toxoplasma gondii (protozoan parasite) are well studied organisms that stimulate a characteristic Th2 and Th1 response, respectively. Several studies have demonstrated reduced inflammatory cytokine responses in animals co-infected with such organisms.

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Background And Objectives: Pediatric fellows across all subspecialties are interested in global health (GH). Little is known about how GH is incorporated into Pediatric Hospital Medicine (PHM) fellowships. Our objective was to examine the current landscape of GH education in PHM fellowships.

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