Publications by authors named "A Lembcke"

Computed tomography (CT) is used as a valuable tool for device selection for interventional therapy in tricuspid regurgitation (TR). We aimed to evaluate predictors of TR reduction using CT and automated deep learning algorithms. Patients with severe to torrential TR and CTs prior to either percutaneous annuloplasty (PA) or tricuspid transcatheter edge-to-edge repair (T-TEER) were enrolled.

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Article Synopsis
  • Kawasaki Disease (KD) is increasingly affecting adults, leading to more women with the condition considering pregnancy, yet data on pregnancy outcomes in these patients are scarce.
  • A case study of a 30-year-old woman with a history of KD and cardiac issues shows her pregnancy was initially smooth but complicated by breast cancer at 31 weeks, requiring neoadjuvant chemotherapy that was well-tolerated by both mother and fetus.
  • The case highlights the importance of careful management of pregnancy with KD and associated conditions, along with the necessity for interdisciplinary collaboration to ensure the best outcomes for both mother and baby.
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Background: In most cases of transcatheter valve embolization and migration (TVEM), the embolized valve remains in the aorta after implantation of a second valve into the aortic root. There is little data on potential late complications such as valve thrombosis or aortic wall alterations by embolized valves.

Aims: The aim of this study was to analyze the incidence of TVEM in a large cohort of patients undergoing transcatheter aortic valve implantation (TAVI) and to examine embolized valves by computed tomography (CT) late after TAVI.

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The health impact of the COVID-19 pandemic across OECD (Organisation for Economic Co-operation and Development) and European regions has been strikingly uneven. In 2020, excess mortality rates in the hardest-hit regions were, on average, 17 percentage points higher than those in the least affected regions of the same country. This paper shows that low health system capacity, followed by population density, air pollution, the share of elderly people, and low institutional quality were associated with higher excess mortality during the first year of the pandemic.

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In patients with aortic stenosis, computed tomography (CT) provides important information about cardiovascular anatomy for treatment planning but is limited in determining relevant hemodynamic parameters such as the transvalvular pressure gradient (TPG). In the present study, we aimed to validate a reduced-order model method for assessing TPG in aortic stenosis using CT data. TPG was calculated using a reduced-order model requiring the patient-specific peak-systolic aortic flow rate (Q) and the aortic valve area (AVA).

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