Association between post-operative hPG (circulating progastrin) detectable level and worse prognosis in glioblastoma.

Background: Patients with glioblastomas have a dismal prognosis, and there is no circulating predictive or prognostic biomarker. Circulating progastrin, hPG, is a tumor-promoting peptide present in the blood of patients with various cancers that has been shown to have prognostic value. We evaluated the prognostic value of plasma hPG in patients with isocitrate dehydrogenase-wild type glioblastoma after surgery.

Plasma hPG (Circulating Progastrin) as a Novel Prognostic Biomarker for early-stage breast cancer in a breast cancer cohort.

Background: Recurrence and metastases are still frequent outcomes after initial tumour control in women diagnosed with breast cancer. Although therapies are selected based on tumour characteristics measured at baseline, prognostic biomarkers can identify those at risk of poor outcomes. Circulating progastrin or hPG was found to be associated with survival outcomes in renal and hepatocellular carcinomas and was a plausible prognostic biomarker for breast cancer.

Distinctions in the making: A theoretical discussion of youth and cultural capital.

The aim of this paper is to address the dynamics of contemporary cultural capital by interrogating what counts for young people as valuable cultural resources. Considerable support is given in later scholarship for Bourdieu's model of the social space, as the overall volume of economic and cultural capital combined is regularly found to be the most important axis of opposition, just as in Bourdieu's work Distinction. Yet, while Bourdieu found the second axis to be structured by an opposition between those with cultural rather than economic capital, and vice versa, many later studies instead find oppositions between the young and the old to structure the second axis.

Supplementation with omega-3 or omega-6 fatty acids attenuates platelet reactivity in postmenopausal women.

Postmenopausal women are at increased risk for a cardiovascular event due to platelet hyperactivity. There is evidence suggesting that ω-3 polyunsaturated fatty acids (PUFAs) and ω-6 PUFAs have cardioprotective effects in these women. However, a mechanistic understanding of how these fatty acids regulate platelet function is unknown.

hPG (Circulating Progastrin), a Novel Blood-Based Biomarker for Detection of Poorly Differentiated Neuroendocrine Carcinoma and Well Differentiated Neuroendocrine Tumors.

Current blood-based biomarkers for neuroendocrine neoplasms (NENs) lack both sensitivity and specificity. Human circulating progastrin (hPG) is a novel biomarker that can be easily measured in plasma by ELISA. This study is the first to examine hPG in NENs.