Publications by authors named "A Lavergne"

Article Synopsis
  • - cVDPV3s were found in wastewater samples in French Guiana between May and August 2024, indicating the detection of circulating type 3 vaccine-derived polioviruses.
  • - The oral polio vaccine isn’t used in the area, suggesting these polioviruses may have been imported or derived from a vaccine strain.
  • - This situation emphasizes the need for environmental monitoring to catch and eliminate any hidden poliovirus activity, which is vital for the global polio eradication effort.
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Article Synopsis
  • Bacterial endosymbionts are common in mosquitoes and can influence reproduction and block virus transmission, making them potential tools for vector control.
  • In French Guiana, a study found that 65.9% of tested mosquito species carried these bacteria, though the major dengue vector showed no infection.
  • The research provides insights into the prevalence and types of these bacteria, which can inform future strategies for controlling disease-carrying mosquito populations in the region.
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Article Synopsis
  • Research indicates that stimulating pancreatic beta cell regeneration could help treat diabetes, utilizing zebrafish which can effectively regenerate these cells from ductal progenitors.
  • A study identified the protein phosphatase calcineurin (CaN) as a significant factor influencing this regeneration process, where overexpressing CaN hindered the regenerative response while inhibiting it promoted beta cell regeneration.
  • Interestingly, the increased proliferation of progenitor cells due to CaN inhibition was linked to their eventual exhaustion, suggesting that CaN plays a crucial role in balancing cell proliferation and differentiation to maintain an adequate pool of progenitors for beta cell regeneration.
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Pathogens transmitted by mosquitoes (Diptera, Culicidae) in sylvatic or urban cycles involve wild or domestic animals and humans, driven by various mosquito species with distinct host preferences. Understanding mosquito-host associations is crucial for ecological insights and pathogen surveillance. In this study, we analyzed mosquito blood meals from coastal French Guiana by amplifying and sequencing host DNA from blood-fed females.

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French Guiana experienced an unprecedented dengue epidemic during 2023-2024. Prior to the 2023-2024 outbreak in French Guiana, DENV-3 had not circulated in an epidemic manner since 2005. We therefore studied retrospectively the strains circulating in the French Territories of the Americas (FTA)-French Guiana, Guadeloupe, and Martinique-from the 2000s to the current epidemic.

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