Publications by authors named "A Lauten"
Objective: To investigate the ongoing parvovirus B19 (B19V) outbreak among pregnant women in Germany and its connection to the coronavirus disease 2019 (COVID-19) pandemic.
Methods: This retrospective cohort study analyzed anonymous data regarding serologically confirmed B19V infections during pregnancy between January 2014 and April 2024 across 13 major fetal medicine centers in Germany. We evaluated the yearly frequency of B19V cases, cases that underwent intrauterine transfusion (IUT), cases presenting with hydrops fetalis and cases of intrauterine fetal death (IUFD) related to B19V infection, and stratified these variables by event occurrence < 20 weeks' gestation or ≥ 20 weeks' gestation.
Background: Tricuspid transcatheter edge-to-edge repair (T-TEER) has emerged as a treatment option for patients with severe tricuspid regurgitation (TR). However, randomized trials have not shown a survival benefit, possibly because of the inclusion of patients in an early or too advanced disease stage.
Objectives: The authors sought to investigate the association between disease stage and outcomes following T-TEER.
Article Synopsis
- The Supraflex Cruz sirolimus-eluting stent (SES) shows promising early healing properties and is effective for patients at high bleeding risk (HBR) undergoing percutaneous coronary intervention (PCI).
- A study involving 1203 patients, with 38.7% classified as HBR, measured safety and efficacy through a composite endpoint, finding higher cardiovascular events in HBR patients compared to non-HBR ones (8.1% vs. 4.4%).
- Results confirmed the Supraflex Cruz's non-inferiority in both HBR and non-HBR groups when compared to established stent trials, indicating it is a safe option for this patient population.
Article Synopsis
- * It found that patients with mild residual TR had an 85% survival rate, while those with moderate and severe TR had significantly lower rates of 70% and 44%, respectively.
- * The research emphasizes the need for a more detailed classification of TR severity to better predict patient outcomes and highlights the goal of achieving at least mild to moderate residual TR for successful interventions.
Background: To analyze the risk of postoperative bleeding following endoscopic endonasal transsphenoidal surgery (EETS) for treatment of pituitary adenomas (PA) in patients with short-term discontinuation of low-dose aspirin, if required for prevention of artherothrombotic disease (ATD).
Methods: Patients with preoperative aspirin medication were identified in this single-center retrospective analysis of consecutive patients with PA, who underwent EETS between December 2008 and June 2022. Aspirin was discontinued perioperatively less than 2 days, > 2 and < 4 days, and > 4 and < 7 days according to the assumed risk of perioperative ATD.