Publications by authors named "A Lauretta"
Background: Diverting ileostomy is a common procedure in rectal cancer surgery, but it is sometimes associated with a nonnegligible rate of complications. The primary aim of this study was to analyze the incidence and types of stoma-related complications for ileostomy creation after rectal cancer resection. The secondary aims were to report the indications, the technical details, and the efficacy of stoma care provided by ostomy nurses.
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- * It used the Delphi method to gather expert opinions, leading to consensus on key aspects such as when to prescribe TAI and the techniques to use, ultimately establishing guidelines that clinicians and nurses can follow.
- * The resulting protocol aims to improve patient care and outcomes by addressing technical challenges and providing clear recommendations for the use of TAI in these patients.
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- Anthracyclines are effective for treating metastatic soft tissue sarcoma (mSTS), but they can be too toxic for frail elderly patients, making trabectedin a potentially safer alternative.
- This study focused on 11 elderly patients (age ≥70) with mSTS receiving trabectedin as their first treatment, monitoring their dosage and outcomes closely.
- Results showed a median progression-free survival of 77 days and overall survival of 397 days, with a 43% rate of severe toxicity, emphasizing trabectedin's role in providing a treatment option with manageable side effects for elderly patients.
Article Synopsis
- The trauma mortality rate is higher in elderly patients due to age-related physiological changes and frailty, necessitating specialized management guidelines to improve outcomes and minimize unnecessary procedures.
- Expert surgeons reviewed literature and developed evidence-based recommendations for geriatric trauma care, focusing on frailty assessment, early activation of trauma protocols, and multimodal pain management.
- Key practices include administering antibiotics selectively for certain traumatic injuries, ensuring timely venous thromboembolism prevention, and involving palliative care teams to address end-of-life discussions with a holistic approach.