Publications by authors named "A Landier"
As other European countries, France is experiencing a resurgence of pertussis in 2024. Between 1 January and 31 May 2024, 5,616 (24.9%) positive qPCR tests were identified, following a 3-year period of almost null incidence.
View Article and Find Full Text PDFBetween March and October 2022, a peak of detection of by qPCR, real-time PCR was observed in France. Whether this peak was due to resurgence from previous circulating lineages or reintroduction into the country was unknown. The objective of this study is to understand transient increase observed in France in 2022 whereas it had virtually stopped being reported since the start of the COVID-19 pandemic in 2020.
View Article and Find Full Text PDFThe Corynebacterium diphtheriae species complex comprises seven bacterial species, including Corynebacterium ulcerans, a zoonotic pathogen from multiple animal species. In this work, we characterise phenotypically and genotypically isolates belonging to two C. ulcerans lineages.
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- Bordetella pertussis, the bacteria causing whooping cough, continues to circulate globally despite vaccines, and this study focuses on differences between two fimbrial serotypes, FIM2 and FIM3.
- The research involved analyzing the microbial traits and protein profiles of 19 bacterial isolates, revealing that FIM2 produces more fimbriae and biofilm but is less effective at agglutination and survival in cord blood than FIM3.
- Findings indicate that distinct fimbrial serotypes and their clades are linked to significant differences in virulence factors, which could affect disease spread and prevention strategies.
The genus Bordetella includes bacteria that are found in the environment and/or associated with humans and other animals. A few closely related species, including Bordetella pertussis, are human pathogens that cause diseases such as whooping cough. Here, we present a large database of Bordetella isolates and genomes and develop genotyping systems for the genus and for the B.
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