Publications by authors named "A Lamrani"
Upon parasitic helminth infection, activated intestinal tuft cells secrete interleukin-25 (IL-25), which initiates a type 2 immune response during which lamina propria type 2 innate lymphoid cells (ILC2s) produce IL-13. This causes epithelial remodeling, including tuft cell hyperplasia, the function of which is unknown. We identified a cholinergic effector function of tuft cells, which are the only epithelial cells that expressed choline acetyltransferase (ChAT).
View Article and Find Full Text PDFBackground: The rising prevalence of gluten-related disorders such as celiac disease explains the increased consumption of gluten-free foods (GFF). However, these foods must be safe in terms of both gluten content and contamination by pathogenic microorganisms in order to avoid food poisoning.
Objective: The objective of this study was to assess the microbiological quality of gluten-free meals, naturally gluten free foods, and gluten free-labelled products.
Article Synopsis
- A study evaluated the effectiveness of accelerated partial-breast irradiation (APBI) versus standard whole-breast irradiation (WBI) in 170 early breast cancer patients after surgery, focusing on doses received by organs-at-risk (OAR).
- Results showed that APBI resulted in significantly lower radiation doses to various OARs, including the contralateral breast, lungs, heart, and spinal cord, when compared to WBI.
- The findings suggest that APBI is a safer option for certain patients, as it can reduce the risk of secondary tumors and major cardiac issues.
Gut microbiota imbalance (dysbiosis) is increasingly associated with pathological conditions, both within and outside the gastrointestinal tract. Intestinal Paneth cells are considered to be guardians of the gut microbiota, but the events linking Paneth cell dysfunction with dysbiosis remain unclear. We report a three-step mechanism for dysbiosis initiation.
View Article and Find Full Text PDFObjectives: Neonatal sepsis caused by multidrug-resistant (MDR) bacteria has a high morbidity and mortality, especially in low- and middle-income countries. Here, the molecular mechanisms of multidrug resistance in bacteria responsible for neonatal sepsis were determined.
Methods: From July to December 2019, documented bacteraemia from 524 neonates hospitalised in a neonatal intensive care unit in Morocco were collected.