Centenarians-the way to healthy vascular ageing and longevity: a review from VascAgeNet.

The prevalence of centenarians, people who lived 100 years and longer, is steadily growing in the last decades. This exceptional longevity is based on multifaceted processes influenced by a combination of intrinsic and extrinsic factors such as sex, (epi-)genetic factors, gut microbiota, cellular metabolism, exposure to oxidative stress, immune status, cardiovascular risk factors, environmental factors, and lifestyle behavior. Epidemiologically, the incidence rate of cardiovascular diseases is reduced in healthy centenarians along with late onset of age-related diseases compared with the general aged population.

The Awareness of Methylphenidate and Its Use: Experiences and Perceptions of Medical Students.

Background and objective Over the past decade, the use of psychostimulants typically prescribed for attention-deficit/hyperactivity disorder (ADHD), such as methylphenidate (MP), has become popular among undergraduate students to enhance their academic performance. Despite potential health and legal repercussions, the misuse of these medications has become a significant public health issue, not only in the general population but particularly among students in medical schools across Turkey. This study investigated the prevalence of MP misuse among Turkish medical students and the factors contributing to it.

Antiproliferative effects of hazelnut cell culture extract on the different cancer cell lines.

The increasing incidence of cancer has necessitated the discovery of novel anticancer compound sources. The presence of taxanes in hazelnut cell cultures has promoted new promising pharmacotherapeutic applications. The antiproliferative properties of hazelnut (Corylus avellana cv.

Comparative Morphometric Study of the Occipital Condyle in Class III and Class I Skeletal Malocclusion Patients.

Objectives: Since the formation of skeletal malocclusions is closely linked to general craniofacial development, it is crucial to understand the anatomy and growth patterns of the skull base. This study aimed to assess the morphometry of the occipital condyle (OC) on CBCT scans of Class III skeletal malocclusion subjects and compare the findings with those of skeletal Class I malocclusion subjects.

Methods: A retrospective analysis was performed on CBCT images based on predefined inclusion and exclusion criteria.