Publications by authors named "A Lacquaniti"
Acute kidney injury (AKI) is associated with long-term consequences and poor outcomes in the neonatal intensive care unit. Its precocious diagnosis represents one of the hardest challenges in clinical practice due to the lack of sensitive and specific biomarkers. Currently, neonatal AKI is defined with urinary markers and serum creatinine (sCr), with limitations in early detection and individual treatment.
View Article and Find Full Text PDFSurgical aortic valve replacement (SAVR) is often complicated by acute kidney injury (AKI). Identifying patients at risk of AKI is important to start nephroprotective strategies or renal replacement therapy (RRT). This study investigated the incidence and risk factors of post-operative AKI in SAVR patients.
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- - Blood purification, specifically using Seraph-100, shows promise in treating sepsis by improving inflammation and controlling an overactive immune response, with a focus on its binding efficacy to several bacteria.
- - A series of experiments using fluorescence-activated cell sorting (FACS) demonstrated a significant 78.77% reduction in bacterial load within the first 30 minutes of treatment, and different bacterial strains exhibited varying growth rates and affinities.
- - Post-experiment analysis revealed that the Seraph-100 filter captured roughly 50% of the bacteria at the top, with the total bacterial count remaining consistent, thereby confirming its effectiveness in reducing infections during hemoperfusion therapy.
: Several studies revealed a relation between abnormal cardiac remodeling and glomerular filtration rate (GFR) decline, but there are limited data regarding echocardiographic changes in chronic kidney disease (CKD). This study evaluated the abnormal cardiac structures characterizing patients with CKD, assessing the independent association between echocardiographic parameters and the risk of decline in renal function. In total, 160 patients with CKD were studied.
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- The study compares the effectiveness of surgical treatments and continuous antibiotic prophylaxis (CAP) for children with vesicoureteral reflux (VUR) by analyzing outcomes like febrile urinary tract infections (UTIs) and VUR resolution.
- Among the 350 pediatric patients, recurrent febrile UTIs were more common in those with higher grades of VUR (III and V) post-surgery, while CAP showed better results in preventing scarring and UTIs.
- The findings highlight that younger patients with late-onset VUR often experience persistent issues, and the study aims to identify factors that predict the success or failure of each treatment method for VUR.