Publications by authors named "A Labat"

Recombination suppression can evolve in sex or mating-type chromosomes, or in autosomal supergenes, with different haplotypes being maintained by balancing selection. In the invasive chestnut blight fungus Cryphonectria parasitica, a genomic region was suggested to lack recombination and to be partially physically linked to the mating-type (MAT) locus based on segregation analyses. Using hundreds of available C.

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Background: Hypertension is one of the main risk factors for cardiovascular disease impacting over a billion people worldwide. Work environment factors could adversely affect workers' cardiovascular health, including contributing to hypertension. Healthcare workers who treat patients are also affected.

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Article Synopsis
  • A wide variety of mating systems exist in nature, with Basidiomycete fungi typically having two mating-type loci (HD and PR) that control compatibility, usually located on different chromosomes.
  • In certain Microbotryum anther-smut fungi, these loci have undergone chromosomal fusions, leading to large regions without recombination and evolutionary changes.
  • Research on three Microbotryum species revealed that the HD genes lost their function in controlling mating compatibility, with mating now relying solely on the PR factor, showcasing a significant evolutionary transition.
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Background: Mitral valve diseases are a common medical condition, and surgery is the most used therapeutic approach. The need for less invasive interventions led to the development of transcatheter valve implantation in high-risk patients. However, the treatment to the dysfunctions of these prosthetic valves is still uncertain, and the yield and safety of repeated transcatheter valve implantations remain unclear.

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Background: Hypertension remains one of the leading risk factors for cardiovascular disease. Contrasting with the high-income countries where the rates of hypertension decline, it increases in Sub-Saharan African countries. The age group most affected by hypertension is the working population.

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