Publications by authors named "A LaCruz"

Article Synopsis
  • - Serological tests are crucial for detecting autoantibodies (autoAbs) in autoimmune neuropathies (AN) and myasthenia gravis (MG), serving as biomarkers for diagnosis and treatment.
  • - A comparison of autoAb testing across 27 Spanish diagnostic laboratories revealed significant variability in results, with particularly low sensitivity for anti-ganglioside and anti-MAG autoAb detection.
  • - The study emphasizes the urgent need for standardization in autoAbs testing to improve reliability and accuracy in clinical applications for AN and MG.
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Waterborne polyurethane-urea dispersions (WPUD), which are based on fully biobased amorphous polyester polyol and isophorone diisocyanate (IPDI), have been successfully synthesized obtaining a finishing agent that provides textiles with an enhanced hydrophobicity and water column. Grafting of trans-cyclohexanediol isobutyl POSS (POSS-OH) to the biobased polymer backbone has also been investigated for the first time and its properties compared to a standard chain extender, 1,3-propanediol (PDO). The chemical structure of WPUD has been characterized by Fourier-transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR).

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Waterborne polyurethane-urea dispersions (WPUD), which are based on 100% bio-based semi-crystalline polyester polyol and isophorone diisocyanate, have been successfully synthesized and doped with single-walled carbon nanotubes (SWCNT) to obtain a finishing agent that provides textiles with multifunctional properties. The chemical structure of WPUD has been characterized by Fourier-transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR). The thermal properties have been evaluated by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and dynamic mechanical thermal analysis (DMTA).

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Hypertrophic cardiomyopathy (HCM) is a cardiac disease, characterized by marked hypertrophy and genetic variability. HCM has been associated with sarcomere protein mutations, being cardiac beta-myosin (coded by the MYH7 gene) and myosin binding protein C (coded by the MYBPC3 gene) the most frequently affected proteins. As in Venezuela only the clinical analysis are performed in HCM patients, we decided to search for genetic variations in the MYH7 gene.

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Article Synopsis
  • The study examined how olanzapine affects insulin counter-regulatory factors, fibrinogen, and C-reactive protein levels in patients with chronic schizophrenia, along with the impact of metformin on these factors.
  • 37 patients were given olanzapine for 14 weeks, with 19 receiving metformin and 18 receiving a placebo in a randomized trial.
  • Results showed decreased levels of cortisol, tumor necrosis factor-alpha, and fibrinogen in both groups, with metformin showing a potential beneficial effect despite not preventing weight gain associated with olanzapine.
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