Publications by authors named "A La Boria"
Article Synopsis
- - Melanoma of the external auditory canal (EAC) is rare and poorly understood, with this systematic review analyzing 30 patient cases to provide insights on management and survival, adhering to PRISMA 2020 guidelines.
- - The review finds that Breslow thickness's influence on surgical decisions is unclear due to insufficient data, and both sentinel lymph node biopsy and adjuvant therapies are rarely used, highlighting the need for standardized treatment protocols.
- - Overall, patients show a 50% survival rate at 5 years, indicating that EAC melanoma is an aggressive cancer, with surgical options like wide local excision and lateral temporal bone resection as primary treatments for those without metastatic disease.
(1) Background: Proton therapy, a precise form of radiation treatment, can be significantly affected by variations in bowel content. The purpose was to identify the most beneficial gantry angles that minimize deviations from the treatment plan quality, thus enhancing the safety and efficacy of proton therapy for Wilms' tumor patients. (2) Methods: Thirteen patients with Wilms' tumor, enrolled in the SJWT21 clinical trial, underwent proton therapy.
View Article and Find Full Text PDFThis dosimetric study is intended to lower the modulation factor in lung SBRT plans generated in the Eclipse TPS that could replace highly modulated plans that are prone to the interplay effect.Twenty clinical lung SBRT plans with high modulation factors (≥4) were replanned in Varian Eclipse TPS version 15.5 utilizing 2 mm craniocaudal and 1 mm axial block margins followed by light optimization in order to reduce modulation.
View Article and Find Full Text PDFObjective: The prognostic significance of the resection margins is still subject of conflicting opinions. The purpose of this paper is to report the results of a study on the margins in carcinoma of the oral cavity, oro-hypopharynx and larynx.
Methods: A multicentre prospective study was carried out between 2015 and 2018 with the participation of 10 Italian reference hospitals.
Article Synopsis
- Lp(a) is a type of LDL particle linked to cardiovascular risk, influenced by variations in the apo(a) protein structure, specifically the number of KIV-2 repeats.
- Researchers studied four Lp(a) variants (K20, K24, K25, K29) to see if their physical properties at interfaces could indicate risk levels.
- Results showed that while all variants formed similar adsorbed layers, differences in surface pressure allowed for a clear distinction between low-risk (K20, K24) and high-risk (K25, K29) groups, suggesting potential for these findings to enhance cardiovascular risk assessment and precision medicine.