Publications by authors named "A L. Greenbaum"
Objective: Percutaneous vegetation debulking has been reported to treat tricuspid valve infective endocarditis (TVIE), but data on feasibility compared with conventional surgical strategies are limited. We aimed to compare short-term outcomes of suction debulking with partial venovenous bypass to conventional open surgery in this population.
Methods: This was a single-center, retrospective study that included all patients with isolated TVIE who underwent suction debulking with partial venovenous bypass or tricuspid valve surgery between January 2010 and December 2022.
Background: Lifetime treatment of aortic valve disease is a matter of increasing debate. Although the risks of a second aortic valve intervention are recognized, little attention has been given to the challenges of a third.
Objectives: This study delves into the clinical characteristics, indications, and outcomes of patients undergoing 3 aortic valve interventions.
Novel Porcine Model Reveals Two Distinct LGR5 Cell Types During Lung Development and Homeostasis.
Am J Respir Cell Mol Biol
November 2024
Article Synopsis
- Cells expressing LGR5 are crucial for homeostasis and regeneration in various organs, but their function in the human lung has not been well studied, especially compared to findings from mouse models.
- Utilizing a new transgenic pig model, researchers identified two significant populations of LGR5 cells in the lung that are similar to those found in humans but not in mice.
- The study reveals that LGR5 expression occurs transiently in fetal lung progenitor cells and is absent in postnatal lungs but can be reactivated in specific organoid models, highlighting the complex roles of LGR5 cells in lung development and potential for repair.
Article Synopsis
- Work-related musculoskeletal injuries are common in general surgery residents, leading to chronic pain and a lack of ergonomic training in residency programs.
- A study found that a significant portion of residents experienced pain, primarily in the neck and shoulders, while very few utilized ergonomic breaks during surgeries.
- The research highlights the need for improved ergonomic practices and initiatives in surgical training, as the observations indicated poor posture among residents during procedures.