Zh Nevropatol Psikhiatr Im S S Korsakova
June 1989
Conditioned reflexes, behavior and cerebral protein metabolism were studied in the offspring of rats subjected to prenatal exposure to ethanol. The open field behavior features are described as well as impaired retaining of conditioned reflexes of passive and active avoidance with an increased sensitivity to acoustic stimulation. Total protein content and its fractions were changed as well as labeled amino acids incorporation into the proteins in different brain structures.
View Article and Find Full Text PDFWhite rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy. [3H]muscimol binding level of neocortex synaptosomal membranes was significantly higher in their offsprings as compared with the control ones. Possible ways of GABA-ergic system malformations are discussed.
View Article and Find Full Text PDFThe authors studied behavioral responses, conditioned reflexes and indices of protein synthesis in the structures of the brain in the progeny of female rats which received ethanol during the period of lactation.
View Article and Find Full Text PDFWhite rats were subjected to ethanol exposure during 5-20 days of pregnancy. 3H-muscimol binding with synaptosomal neocortex membranes yielded from two month age offsprings was studied. 3H-muscimol binding level for experimental animals was 27% more than for control ones.
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