Integrating Ambulatory Care Pharmacists Into Value-Based Primary Care: A Scalable Solution to Chronic Disease.

Introduction/objectives: Patients living with chronic diseases require more medical attention, including more visits to primary care. However, primary care providers are overburdened, and this specialty is attracting fewer new providers than before. Clinical pharmacists can augment these efforts by improving disease state control.

Weak fault feature extraction method of rolling bearing based on wavelet packet decomposition and optimized MCKD.

The early fault characteristics of rolling bearings are weak, especially in a strong noise environment, which are more difficult to extract; therefore, a method based on wavelet packet decomposition, multi-verse optimizer, and maximum correlated kurtosis deconvolution for weak fault feature extraction of rolling bearings is proposed. First, the original vibration signal is decomposed using wavelet packet decomposition, followed by proposing a signal reconstruction method combining the Pearson correlation coefficient and energy ratio to effectively remove noise from the original signal. Second, the parameters L and M of Maximum Correlated Kurtosis Deconvolution (MCKD) are optimized using the multi-verse optimizer algorithm to obtain optimal filter settings.

Impact of presurgical systemic therapy on perioperative outcomes of renal cell carcinoma with inferior vena cava tumor thrombus.

Background: Surgery for inferior vena cava tumor thrombus (IVC-TT) in patients with renal cell carcinoma (RCC) is highly invasive and is associated with perioperative mortality. This study aimed to assess the efficacy of presurgical systemic therapy (PT) on perioperative outcomes in RCC patients with IVC-TT.

Methods: A total of 68 patients with right-sided RCC and level ≥ II IVC-TT were included in this study.

Augmented reality for epilepsy surgery: Examining usability and efficacy in presurgical planning.

Objective: The aim of this paper was to visualize 3-dimensional (3-D) brain and electrode placement data for epilepsy surgery within an augmented reality (AR) environment using a wearable headset, with the ultimate goal of enhancing presurgical planning for epilepsy surgery and understanding the efficiency and utility of such a program in a clinical setting. The evaluation process for surgical intervention in epilepsy cases involves a series of extensive tests, including EEG, MRI, PET, SPECT, and fMRI. A second phase of assessment incorporates the placement of depth electrodes within the brain to record seizure activity.

COVID-19 vaccination and cerebral small vessel disease progression-A prospective cohort study.

Objectives: The association between SARS-CoV-2 spike protein and cerebrovascular diseases raised a concern of cerebrovascular safety of COVID-19 vaccines. We aimed to determine the risk of radiologic cerebral small vessel disease (cSVD) progression with BNT162b2 and CoronaVac.

Methods: In this community-based prospective cohort study, community-dwelling subjects underwent brain magnetic resonance imaging (MRI) before and 4 months after vaccination with BNT162b2 or CoronaVac.