Modulation of long-term memory by delayed administration of the amide of L-pyroglutamyl-D-alanine, a nootropic agent, in spaced and massed training in rats.

The effects of the nootropic agent L-pyroglutamyl-D-alanine amide (given at a dose of 0.5 mg/kg i.p.

[Modulation of the long-term memory by delayed administration of the nootropic agent L-pyroglutamyl-D-alaninamide during spaced and massed training of rats].

L-pyroglutamyl-D-alanine amide significantly enhanced freezing response in the group of rats with massed training and reduced it in the group with spaced training. The control animals revealed a higher freezing response with the spaced training. No differences occurred between the groups in a cue test.

[Immune disorders in patients with purulent necrotic complications of erysipelas].

There were examined 106 patients with purulent-necrotic complications (PNC) of erysipelas and 102 patients without PNC. Significant disorders of the immune status were revealed: the reduction of T-lymphocytes quantity, their subpopulational content dysbalance, the rise of level of a middle- and small-molecular immune complexes. In patients with PNC the immunocorrection conduction is expedient.

[Laboratory methods of prognostication in suppurative complications of erysipelas inflammation].

The dynamics of the leukocyte index of intoxication (LII) and the blood-cell index (BCI) was studied in 2756 patients with erysipelas. Both indexes, raised at the height of the disease, are lowering under the therapy influence. At the purulent-inflammatory complications beginning the LII and BCI level remains high or raises 2-3 days before occurrence of clinical signs of complication.