[The dorsal hippocampus injury influences chronobiological effects of depressants and antidepressants in rats].

The administration of depressant reserpine and antidepressant imipramine in rats is manifested by opposite trends in the chronobiological aspect of behavior. Reserpine disorganizes the circadian locomotion rhythm and increases the rhythmological index of depression in the forced swim test. In contrast, imipramine increases the circadian rhythm contrast and decreases the index of depression.