Publications by authors named "A L Sherman"
Furanocoumarins (FCs) are plant defence compounds derived from the phenylpropanoid pathway via the coumarin umbelliferone that harbour some therapeutic benefits yet are the underlying cause of 'grapefruit-drug interactions' in humans. Most of the pathway genes have not been identified in citrus. We employed a genetic/Omics approach on citrus ancestral species and F1 populations of mandarin × grapefruit and mandarin × pummelo.
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- The introduction discusses challenges in achieving flat closure during oncologic mastectomy in obese patients and introduces the angel wing (AW) technique as a solution.
- A retrospective study at an academic center evaluated the safety of the AW technique by analyzing postoperative arm lymphedema (AL) and decreased range of motion (dROM) in patients who underwent mastectomy with and without this technique.
- Results showed no significant difference in the incidence of AL or dROM between the AW and non-AW groups, suggesting that the AW technique is a safe option for achieving effective surgical outcomes in obese patients postmastectomy.
Background: Most patients with a pediatric rheumatic disease are at increased risk of influenza due to immunosuppressive medication use. Despite initial quality improvement efforts, our influenza vaccination rate plateaued at 72%, which prompted a survey of patients and families to assess provider vaccine recommendations, influenza knowledge, and barriers to influenza vaccination.
Methods: Patients on immunosuppressive medication or their parent were eligible to complete a survey between July 2019 and January 2020.
Introduction: Alternate electrocardiogram acquisition with fewer leads lacks systematic evaluation in children. This study aims to determine if electrocardiograms with fewer leads maintain diagnostic accuracy in paediatrics.
Methods: This is a single-centre review of 200 randomly selected standard 12-lead electrocardiograms from our hospital database (2017-2020) for patients aged 2 weeks to 21 years.
Article Synopsis
- The study investigates the role of one-hour post-load plasma glucose (1 h-PG) levels as an early marker for Type 2 Diabetes (T2D) risk by analyzing a longitudinal cohort over ten years.
- It categorizes participants into three groups based on their initial 1 h-PG levels and measures insulin sensitivity and β-cell function at different stages.
- Results indicate that individuals with higher 1 h-PG levels have a greater risk of developing T2D and experiencing decreased insulin sensitivity and β-cell function, highlighting the potential for early interventions in those with high 1 h-PG but normal glucose tolerance.