Publications by authors named "A L Shafrir"
Background: The risk of thrombosis increases after SARS-CoV-2 infection. This study aimed to assess associations between pre-infection anticoagulant exposure and SARS-CoV-2 infection-related outcomes in a population-based cohort.
Methods: Members of the "Meuhedet" health maintenance organization aged >45 years who tested positive for SARS-CoV-2 infection (03/2020-04/2022) were followed.
Interrupting inflammatory bowel disease therapy: why, who, when and how to consider medication holidays.
Expert Rev Gastroenterol Hepatol
October 2024
Article Synopsis
- Medication holidays in inflammatory bowel disease (IBD) aim to balance effective disease management with cost and quality of life, especially given the chronic nature and treatment side effects of IBD.
- The review discusses the rationale behind medication holidays, how to implement them, potential risks, and strategies to monitor patients and manage relapses.
- Experts emphasize the importance of careful patient selection, ongoing management, and the need for better predictive models and monitoring technologies to safely integrate medication holidays into standard treatment practices.
Ovarian cancer incidence has declined in recent decades, due in part to oral contraceptive (OC) use and tubal ligation. However, intrauterine device (IUD) use has increasingly replaced OC use. As ovarian cancer is an inflammation-related disease, we examined the association of OC use, IUD use, and tubal ligation with plasma levels of C-reactive protein (CRP), interleukin 6, and soluble tumor necrosis factor α receptor 2 in the Nurses' Health Study (NHS) and NHSII.
View Article and Find Full Text PDFObjective: To evaluate the burden of endometriosis-associated pelvic pain (EAPP) on health-related quality of life (HRQoL) among women living in similar socio-economic conditions.
Data Sources: Searches were performed in PubMed and Embase on September 26, 2022. The review was performed in conformity with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis protocol (PRISMA-P) and was registered on PROSPERO (ID: CRD42023370363).