Publications by authors named "A L Ropars"

Article Synopsis
  • Chronic inflammatory diseases are typically treated with anti-inflammatory drugs, but many patients develop resistance, prompting the need for new treatment options.
  • Research on endophytic fungi, which produce various beneficial compounds while living within plants, shows their extracts may offer anti-inflammatory properties.
  • The study found that extracts from five endophytic fungi can counteract inflammation in macrophage cells and identified several potent metabolites, suggesting these fungi could serve as effective alternatives to traditional anti-inflammatory medications.
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Article Synopsis
  • Resistance to standard treatments highlights the need for new therapeutic molecules, particularly from plant specialized metabolites like phenolamides found in tomatoes.
  • The study focused on three major phenolamides, including one specially synthesized for research, to assess their antimicrobial, cytotoxic, and anti-inflammatory effects.
  • Results indicated that while the phenolamides had low to moderate antibacterial activity, they effectively reduced inflammation in macrophages, suggesting their potential as natural alternatives to traditional drugs.
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In this study, phenolic compounds from an aqueous protein by-product from rapeseed meal (RSM) were identified by HPLC-DAD and HPLC-ESI-MS, including sinapine, sinapic acid, sinapoyl glucose, and 1,2-di-sinapoyl gentibiose. The main phenolic compound in this by-product was sinapine. We also performed acid hydrolysis to convert sinapine, and sinapic acid derivatives present in the permeate, to sinapic acid.

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The aim of this study was to valorize liquid effluent from the sunflower protein isolate process by extracting phenolic compounds it contains. To do so, XAD7 resin was used. A multicriteria optimization methodology based on design of experiments showed the optimal conditions were adsorption flow rate of 15 BV/h at pH 2.

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Phenolamides constitute a family of metabolites, widely represented in the plant kingdom, that can be found in all plant organs with a predominance in flowers and pollen grains. They represent a large and structurally diverse family, resulting from the association of phenolic acids with aliphatic or aromatic amines. Initially revealed as active compounds in several medicinal plant extracts, phenolamides have been extensively studied for their health-promoting and pharmacological properties.

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