Publications by authors named "A L Nikonova"
Introduction: The h-index measures researchers' productivity by assessing simultaneously the number of publications and citations. We aimed to assess the factors that could influence h-index for hematologists practicing in academic institutions in Canada.
Methods: We identified universities with a hematology residency training programs/fellowships using the Canadian Resident Matching Service (CaRMS) website.
[The multidirectional effects of thrombin and the possibility of their control in neurology].
Zh Nevrol Psikhiatr Im S S Korsakova
March 2024
The review presents the main physiological functions of thrombin. The procoagulant and anticoagulant activities of the key serine protease are discussed in both physiological and pathological conditions of hemostasis. The involvement of thrombin in atherogenesis, as well as its role as a mediator of vascular dysfunction and inflammation in both the peripheral and central nervous system, is highlighted.
View Article and Find Full Text PDFBackground: IgE cross-sensitization to major birch pollen allergen Bet v 1 and pathogenesis-related (PR10) plant food allergens is responsible for the pollen-food allergy syndrome.
Methods: We designed a recombinant protein, AB-PreS, consisting of non-allergenic peptides derived from the IgE-binding sites of Bet v 1 and the cross-reactive apple allergen, Mal d 1, fused to the PreS domain of HBV surface protein as immunological carrier. AB-PreS was expressed in E.
Article Synopsis
- Colorectal cancer (CRC) is a common and serious cancer in the U.S., affecting about 135,000 people each year and causing around 50,000 deaths.
- Some people with a genetic disease called autosomal dominant polycystic kidney disease (ADPKD), which affects kidneys, might have a lower chance of getting CRC.
- Studies using mice show that when the gene PKD1 is missing, it can reduce the risk and growth of CRC, possibly helping us understand how genetics influence this type of cancer.
Article Synopsis
- Rapid virus identification techniques are essential due to global epidemics, with existing methods like PCR being reliable but slow, and antibody-based strips being fast but less reliable.
- A new multiplex lithographic SERS aptasensor has been developed for quick detection of multiple respiratory viruses simultaneously, offering results in just 17 minutes.
- This sensor uses four labeled aptamers anchored on a metal surface, allowing for the simultaneous identification of viruses like SARS-CoV-2, influenza A, respiratory syncytial virus, and adenovirus through changes in SERS signals.