Publications by authors named "A L Moulton"

Preoperative Coronavirus Disease 2019 (COVID-19) infections are associated with postoperative adverse outcomes. However, there is limited data on the impact of postoperative COVID-19 infection on postoperative outcomes of common general surgery procedures. To evaluate the impact of postoperative COVID-19 diagnosis on laparoscopic cholecystectomy outcomes.

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Background & Aims: In phase 2 studies, efruxifermin, an Fc-FGF21 analog, significantly reduced steatohepatitis and fibrosis in patients with non-alcoholic steatohepatitis, now called metabolic dysfunction-associated steatohepatitis (MASH), for which there is no approved treatment. Type 2 diabetes (T2D) and obesity are prevalent among patients with MASH and increasingly treated with glucagon-like peptide-1 receptor agonists (GLP-1RAs). This study evaluated the safety and efficacy of efruxifermin in patients with MASH, fibrosis, and T2D taking a GLP-1RA.

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Article Synopsis
  • The COVID-19 pandemic worsened healthcare access and increased vaccine hesitancy, prompting a student-led vaccination program in an emergency department aimed at improving vaccine uptake.
  • The program included medical and pharmacy student volunteers who screened patients and provided education to address vaccine concerns, resulting in a slight increase in vaccine acceptance rates post-education.
  • Key findings indicated the major reasons for hesitancy were concerns about side effects, and factors like age and race influenced acceptance; implementation faced challenges but was supported by student engagement and public health efforts.
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This article reports on an assessment of the value of 4 widely recognized standards of health sector emergency preparedness as predictors of effective preparedness for, and response to, the COVID-19 pandemic in the United States. The standards are sponsored by the National Health Security Preparedness Index (NHSPI), the Trust for America's Health (TFAH), the Emergency Management Accreditation Program (EMAP), and the Public Health Accreditation Board (PHAB). The measure of effectiveness was states' cumulative COVID-19 deaths per 100,000 population, from January 21, 2020, through January 20, 2022.

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