Intra- and Postoperative Complications in 4565 vNOTES Hysterectomies: International Registry Cohort Study.

Objective: To present the rates of intra- and postoperative complications and conversions in a large cohort of unselected vNOTES hysterectomies, performed by surgeons with different levels of expertise.

Design: International register-based cohort study.

Setting: Hysterectomies in the iNOTESs registry, 2015 to January 2024, performed by 201 surgeons from multiple countries.

Signaling (in)tolerance: Social evaluation and metaethical relativism and objectivism.

Prior work has established that laypeople do not consistently treat moral questions as being objectively true or as merely true relative to different perspectives. Rather, these metaethical judgments vary dramatically across moral issues and in response to different social influences. We offer a potential explanation by examining how objectivists and relativists are evaluated in different contexts.

Mutational spectrum of breast cancer by shallow whole-genome sequencing of cfDNA and tumor gene panel analysis.

Breast cancer (BC) has different molecular subgroups related to different risks and treatments. Tumor biopsies for BC detection are invasive and may not reflect tumor heterogeneity. Liquid biopsies have become relevant because they might overcome these limitations.

Effect of Preoperative Bilateral Ultrasound-Guided Quadratus Lumborum Nerve Block on Quality of Recovery After Minimally Invasive Hysterectomy in an Enhanced Recovery After Surgery (ERAS) Setting.

Study Objective: To assess the effect of preoperative bilateral ultrasound-guided quadratus lumborum nerve block (QLB) on quality of recovery after minimally invasive hysterectomy, in an enhanced recovery after surgery setting.

Design: Randomized, controlled, double-blinded trial (Canadian Task Force level I).

Setting: University-affiliated tertiary medical center.

Excess use of surgical supplies in minimally invasive benign gynecology surgery: an observational study.

Background: Single-use materials and equipment are regularly opened by the surgical team during procedures but left unused, potentially resulting in superfluous costs and excess environmental waste.

Objective: This study aimed to estimate the excess use of surgical supplies in minimally invasive benign gynecologic surgeries.

Study Design: This is a prospective observational study conducted at a university-affiliated single tertiary medical center.