Insulinotropic and anti-obesity properties of ethno-medicinal plants: pharmacology-based and predictions.

The herbal extracts of four traditional plants; namely leaves, fruits leaves, and seeds, were identified for their main constituents using UHPLC/QTOF-MS/MS. Then, a pharmacology-based analysis and molecular docking verification were established targeting the evaluation of each individual herbal extract for their antidiabetic/anti-obesity potential besides their safety. Streptozotocin-induced diabetic rats were used to evaluate antiobesity and insulinotropic effects against insulin (10 U/Kg, IP) and metformin (100 mg/Kg, per oral) as standard regimens.

A Comparison of Endoscopic and Surgical Gastrojejunostomy in Patients with Malignant Gastric Outlet Obstruction: A National Cohort Analysis (2016-2020).

Background And Aims: Malignant gastric outlet obstruction (MGOO) is an unfortunate complication of advanced upper gastrointestinal malignancies. Historically, surgical gastrojejunostomy has been the procedure of choice to achieve enteral bypass. Recently, endoscopic techniques have gained popularity in the management of MGOO.

Women and Peace-Building: A Case Study of the Guji-Gedio Conflict in Southern Ethiopia.

This study examines the critical roles of women in post-conflict peace-building, with a particular focus on the Guji-Gedio conflict in southern Ethiopia. Using a qualitative research approach that integrates primary and secondary data, the study draws insights from 61 participants through key informant interviews, in-depth discussions with community members, and focus group sessions with women. The findings reveal that, despite enduring significant hardships during conflict, women's contributions to peace-building are severely restricted by entrenched patriarchal norms, traditional gender expectations, and limited access to education.

Vitamin D augments insulin secretion via calcium influx and upregulation of voltage calcium channels: Findings from INS-1 cells and human islets.

Vitamin D (VD) has been implicated in regulating insulin secretion and pancreatic β-cell function. Yet, the underlying molecular mechanism of VD in glucose homeostasis is not fully understood. This study investigates the effect of VD in regulating insulin secretion and pancreatic β-cell function.

The quality of academic life and its relationship with academic passion among university students.

Background: At a time prioritizing the comprehensive growth and welfare of university students, grasping the profound importance of both the quality of academic life and the intricacies of academic passion emerges as crucial for educators, administrators, and policymakers. This research investigates the levels of academic life quality and academic passion among university students, aiming to uncover the intricate relationship between these dimensions. Additionally, the study explores the feasibility of predicting academic life quality based on academic passion.