Publications by authors named "A L Michalowitz"

Mycosis fungoides (MF) is defined as the most common cutaneous T‑cell lymphoma (CTCL). The bullous form is considered one of its numerous variants. Only a few cases of this rare entity have been described.

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Localized lymphedema of the genital region is a rare medical condition. It is named primary lymphedema if caused by a congenital malformation of the lymphatic system. Secondary lymphedemas might be induced by exogenous damage to lymphatic vessels as a result of surgical interventions, obesity, filariasis, radiotherapy or malignancy.

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Article Synopsis
  • Hydrochlorothiazide (HCTZ) is linked to a higher risk of skin cancers such as Atypical fibroxanthoma (AFX) and pleomorphic sarcoma (PDS) compared to squamous cell carcinoma (SCC) and basal cell carcinoma (BCC).
  • A study analyzed data from 146 AFX/PDS patients and 438 SCC/BCC controls over a seven-year period, finding that HCTZ use was significantly more common among AFX/PDS patients (44.5% vs. 25.3%).
  • The findings suggest that HCTZ may be a risk factor for developing AFX/PDS, with diabetes mellitus also linked to an increased risk.
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Anorectal melanomas are a rare malignant type of cancer and pose a diagnostic challenge due to their hidden anatomical location. They are associated with nonspecific clinical symptoms and are therefore often misinterpreted as benign disease. The result is delayed diagnosis in the locally advanced or metastasized stage and an unfavorable prognosis.

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