Publications by authors named "A L Masson"
INhibitor of Growth (ING1-5) proteins are epigenetic readers that target histone acetyltransferase (HAT) or histone deacetylase (HDAC) complexes to the H3K4Me3 mark of active transcription. ING5 targets Moz/Morf and HBO1 HAT complexes that alter acetylation of H3 and H4 core histones, affecting gene expression. Previous experiments in vitro indicated that ING5 functions to maintain stem cell character in normal and in cancer stem cells.
View Article and Find Full Text PDFBackground: Hypereosinophilic syndromes (HES) are a heterogenous group of eosinophilic disorders. To date, only retrospective studies of limited sample-size and/or follow-up duration are available.
Methods: The COHESion study is a national prospective multicenter multidisciplinary cohort recruiting both adults or children with the spectrum of eosinophilic disorders (including reactive HE/HES [HE/HES-R], idiopathic HES [HES-I], lymphocytic HES [HES-L], neoplastic HE/HES [HE/HES-N], HE of unknown significance [HE-US], as well as IgG4-related disease [IgG4RD] or ANCA-negative eosinophilic granulomatosis with polyangiitis [EGPA] overlaps).
Article Synopsis
- The study aimed to analyze characteristics of healthy children with obstructive sleep apnea (OSA-I) and those with OSA and non-syndromic obesity (OSA-II) in France who were treated with CPAP or NIV in 2019.
- Data from a national survey focused on CPAP/NIV initiation criteria, duration, age at initiation, equipment used, settings, and compliance were examined.
- Results showed that OSA-II patients were older at initiation and treated longer than OSA-I patients, with both groups mainly using CPAP, but having similar compliance rates.