Publications by authors named "A L Martinez-Gonzalez"
Background: Recent studies indicate the need to examine how the gut microbiota-brain axis is implicated in pain, sensory reactivity and gastro-intestinal symptoms in autism spectrum disorder (ASD), but no scale exists that assesses all these constructs simultaneously.
Methods: We created a pool of 100 items based on the real-world experience of autistic people, and a multidisciplinary team and stakeholders reduced this pool to 50 items assessing pain, sensory hypersensitivity, and sensory hyposensitivity. In the present study, we present this new assessment tool, the Pain and Sensitivity Reactivity Scale (PSRS), and examine its psychometric properties in a sample of 270 individuals with autism spectrum disorder (ASD; mean age = 9.
Background And Objectives: Hyponatraemia is common in elderly and hospitalised patients, often caused by the syndrome of inappropriate antidiuretic hormone secretion (SIADH). This study evaluates the efficacy and safety of tolvaptan and urea in patients with hyponatraemia and SIADH.
Materials And Methods: An observational cohort study was conducted on 198 patients with SIADH and hyponatraemia (Na+ <135 mmol/L) at the Complejo Hospitalario Universitario de Pontevedra from January 2015 to May 2022.
Article Synopsis
- The zygomatic bone, crucial in facial anatomy, is prone to fractures from impacts like accidents and sports, and zygomatic implants may increase this risk.
- A complex anatomical model using finite-element analysis (FEM) was created to simulate the zygomatic bone's behavior under various impact velocities.
- Results indicated that higher speeds (15 and 20 km/h) caused severe crush fractures, while lower speeds led to less severe local damage, highlighting specific high-stress areas crucial for injury prevention.
Article Synopsis
- The study focuses on comparing the effectiveness and safety of urea versus fluid restriction for treating hyponatraemia caused by SIADH in hospital patients.
- An observational cohort study involving 212 patients showed that urea significantly increased sodium levels more than fluid restriction, with faster normalization of sodium levels (6 days vs. 8 days).
- Additionally, the urea group had a lower 60-day mortality rate (16.1%) compared to the fluid restriction group (32.8%), highlighting urea’s better safety profile.
The present study analyzed the association between anxiety, repetitive behavior and parental stress in individuals with autism from Spain ( = 60, mean age = 8.52, SD = 4.41) and Colombia ( = 58, mean age = 10.
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