The evaluation of health recommender systems: A scoping review.

Background: People often look online for information about health concerns, but the vast amount of available and unregulated content can cause misinformation and potential harm. Health recommender systems (HRSs) can address this issue by recommending personalised health information. Previous research has evaluated individual systems, but there is a lack of reviews synthesising their evaluation findings.

Does Fungal Chitosan Leave Noticeable Traces in Treated Wines?

The use of fungal chitosan as an antiseptic in wine appears as a promising alternative to sulfur dioxide for the elimination of sensitive strains. Nevertheless, its utilization raises the question, "how are the treated wines different from the untreated ones?" Chitosan treatment residues were sought in the oligosaccharide and polysaccharide fractions and among 224 low MW ions (<1800 g·mol) in several wines by using liquid chromatography (size exclusion HPLC or LC-MS) and GC-MS. Standard oenological parameters were also examined as well as possible sensory modifications by a panel of tasters composed of experts and non-experts.

Treat-to-target fixed dose rituximab retreatment versus fixed interval retreatment with disease activity-guided rituximab dose optimisation for patients with rheumatoid arthritis: study protocol for a multicentre randomised controlled superiority trial focusing on long-term disease impact (RITUXERA).

Background: The optimal retreatment strategy with rituximab for rheumatoid arthritis (RA) remains a point of discussion. Depending on local guidelines, rituximab can either be administered at fixed intervals or when losing disease control, balancing therapeutic effectiveness with drug overexposure. However, treatment based on loss of disease control may significantly affect patients' lives, provoking uncertainty and potentially leading to progressive joint damage.