Publications by authors named "A L L Manica"
Schizophrenia (SZ) is a complex, chronic mental disorder characterized by positive symptoms (such as delusions and hallucinations), negative symptoms (including anhedonia, alogia, avolition, and social withdrawal), and cognitive deficits (affecting attention, processing speed, verbal and visuospatial learning, problem-solving, working memory, and mental flexibility). Extensive animal and clinical studies have emphasized the NMDAR hypofunction hypothesis of SZ. Glycine plays a crucial role as an agonist of NMDAR, enhancing the receptor's affinity for glutamate and supporting normal synaptic function and plasticity, that is, signal transmission between neurons.
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- - The study presents a comprehensive whole-genome dataset of 34 Armenian individuals, revealing their population structure and demographic history, showing that eastern, central, and western Armenians are genetically similar.
- - The Sasun population, previously thought to have been heavily influenced by Assyrian genetics, was found to have a unique genetic profile resulting from a recent bottleneck event rather than direct Assyrian ancestry.
- - Research also explores the origins of Armenians, finding no support for Herodotus’ claims of Balkan ancestry, but identifying connections to ancient Neolithic Levantine Farmers and documenting unique mutations related to common health disorders in the community.
Article Synopsis
- Cumulative culture, an important aspect of human evolution, has its origins in the common ancestor shared with chimpanzees, revealing early pathways of cultural transmission.
- The study analyzed genetic markers and cultural traits across four chimpanzee subspecies to understand how their cultural practices developed and remained limited.
- It was found that low inter-group connectivity in chimpanzees led to isolated instances of culture evolving step-by-step, suggesting that social behaviors influenced mobility and cultural exchange among different groups.
Comprehensive Husbandry Protocol for Catfish and Many Other Amazonian Species.
J Am Assoc Lab Anim Sci
September 2024
A variety of fish species have proven instrumental in the investigation of evolution, behavior, ecology, and physiology, among many other fields. Many model systems (e.g.
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