Publications by authors named "A L Kuehn"
Background: This study explores the potential of Artificial Intelligence (AI)-generated social media influencers to disseminate cancer prevention messages. Utilizing a Generative AI (GenAI) application, we created a virtual persona, "Wanda", to promote cancer awareness on Instagram.
Methods: We created five posts, addressing the five most modifiable risk factors for cancer: tobacco consumption, unhealthy diet, sun exposure, alcohol consumption, and Human Papillomavirus (HPV) infection.
Longitudinal Follow-up Reveals Peripheral Immunological Changes Upon Tick Bite in a-Gal-Sensitized Individuals.
J Investig Allergol Clin Immunol
November 2024
Background And Objectives: α-Gal syndrome is characterized by specific IgE (sIgE) antibodies to the carbohydrate galactose-α-1,3-galactose (α-Gal) and delayed onset of allergic symptoms after ingestion of mammalian meat. While tick bites are assumed to mediate sensitization, the immune response to tick bites has not yet been investigated. To investigate the peripheral immune response to tick bites in humans over time.
View Article and Find Full Text PDFExercise-Dependent Codfish Allergy due to Tropomyosin.
J Investig Allergol Clin Immunol
November 2024
Article Synopsis
- Parvalbumins are the main food allergens found in fish meat, with each species having its own unique set of these proteins.
- Allergen codes are assigned based on sequence similarities to the first identified parvalbumin in that species, leading to potential confusion among similar codes across different fish.
- This study aims to simplify the complex genetics of parvalbumins in fish, focusing on gene analysis in common allergenic species like red seabream and chum salmon, while providing a clear naming system for these genes.
Article Synopsis
- The α-Gal syndrome (AGS) is linked to specific IgE antibodies against the carbohydrate galactose-α-1,3-galactose, primarily influenced by tick bites in those exposed to them, like forestry workers in Luxembourg.
- A study analyzed blood samples and questionnaires from 219 forestry employees to determine their IgG and IgE responses to α-Gal compared to other groups, including food-allergic patients.
- Results showed that 21% of forestry employees were sensitized to α-Gal, but both sensitized and non-sensitized exhibited high IgG levels, suggesting that tick bites promote strong immune responses, especially in AGS patients who had the highest IgG levels overall.