Expression of miR-15b-5p and toll-like receptor4 as potential novel diagnostic biomarkers for hepatitis C virus-induced hepatocellular carcinoma.

Objectives: Globally, hepatocellular Carcinoma (HCC) ranks seventh in women's cancer and fifth in men's cancer. Early identification can minimize mortality and morbidity. MicroRNAs and Toll-like receptors have been suggested as potential new biomarkers for HCC; Therefore, we explored Toll-like receptor 4 (TLR-4) and miRNA 15b-5p as new non-invasive HCC biomarkers and early detection approaches.

Sunlight-activated composite TiO-F-V-Mo materials for photodegradation of the organic pollutant methylene blue.

F-doped TiO photocatalyst materials were prepared using solid-state and sol-gel synthesis with varying weight percentages of LiF or NHF. Subsequently, molybdate and vanadium oxide were added to the prepared powders to create composite photocatalysts with reduced bandgap energy, enhancing light absorption in the visible region of the spectrum, which is essential for effective photocatalytic activity using sunlight. The synthesized powders were characterized by thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and specific surface area using the BET method.

Enhanced humidity sensing performance of LiF-doped MgTiO ceramics via spark plasma sintering.

The fabrication of low-porosity ceramics for humidity sensing is crucial to prevent moisture entrapment, which poses significant challenges. Using Spark Plasma Sintering (SPS), we successfully densified fine-grained ceramic materials based on LiF-doped MgTiO, comparing them with conventionally sintered counterparts. Structural and microstructural analyses, employing X-ray diffraction and Scanning Electron Microscopy (SEM), were conducted.

An analysis of paediatric clinical presentations in Northwest Syria and the effect of forced displacement, 2018-2022.

Background: One in six children worldwide lives in a region exposed to armed conflict. In conflicts, children are among the most vulnerable, and at risk of adverse health outcomes. We sought to describe trends in child and adolescent morbidity in northwest Syria (NWS) and understand how forced displacement affects clinical utilisation during the Syrian conflict.

Evaluation of circulating insulin-like growth factor-1, heart-type fatty acid-binding protein, and endotrophin levels as prognostic markers of COVID-19 infection severity.

Background: Coronavirus Disease 2019 (COVID-19) is a worldwide pandemic challenge spreading enormously within a few months. COVID-19 is characterized by the over-activation of the immune system causing cytokine storm. Insulin-like growth factor-1 (IGF-1) pathway can regulate the immune response via interaction with various implicated cytokines.