Theoretical Investigation of the Green-Synthesized Carbon-Based Nanomaterial Potential as Inhibitors of ACE2 for Blocking SARS-CoV-2 Binding.

Since the emergence of SARS-CoV-2 in 2020, the world has faced a global pandemic, emphasizing the urgent need for effective treatments to combat COVID-19. This study explores the use of green-synthesized carbon-based nanomaterials as potential inhibitors of ACE2, a critical receptor for SARS-CoV-2 entry into host cells. Specifically, the study examines four carbon-based nanomaterials, namely, CD1, CD2, CD3, and CD4 in amino, graphitic, pyridinic, and pyrrolic forms, respectively, synthesized from curcumin, to investigate their binding affinity with ACE2.

Green synthesis of copper ions nanoparticles functionalized with rhamnolipid as potential antibacterial agent for pathogenic bacteria.

Copper-based nanoparticles possess broad-spectrum antibacterial activity against both gram-positive and gram-negative bacteria, making them a cost-effective alternative to other metal-based nanoparticles. The development of eco-friendly copper based nanopaticles using biodegradable and non-toxic biosurfactants, such as rhamnolipid is being explored in this study. In the present study, Cu(I)-rhamnolipid nanoparticles (Cu(I)-Rl Nps) was prepared by coprecipitation method.

Potential application of bisoprolol derivative compounds as antihypertensive drugs: synthesis and study.

Two bisoprolol derivatives, -acetyl bisoprolol and -formyl bisoprolol, belonging to the beta-blocker class of antihypertensive drugs, were synthesized using acetylation and formylation reactions. The yields of the reactions were determined to be 32.40% for -acetyl bisoprolol and 20.

In Vitro and Silico Studies on the N-Doped Carbon Dots Potential in ACE2 Expression Modulation.

The alteration of ACE2 expression level, which has been studied in many diseases, makes the topic of ACE2 inducer potential crucial to be explored. The ACE2 inducer could further be designed to control the ACE2 expression level, which is appropriate to a specific case. An in vitro study of well-characterized carbon dots (CDs), made from citric acid and urea, was performed to determine their ability to modulate the ACE2 receptor.

Graphene quantum dots functionalised with rhamnolipid produced from bioconversion of palm kernel oil by BK-AB12MT as a photocatalyst.

Methylene blue (MB) is a common organic dye found in textile wastewater and can harm the environment. Rhamnolipid-functionalized graphene quantum dots (RL-GQDs) are a newly developed eco-friendly photocatalyst to degrade MB. This photocatalyst is synthesized from graphene quantum dots (GQDs) and rhamnolipid.