A Novel Team-Based Approach to Oral Diagnosis Education: Case of the Week.

Background: Traditional oral diagnosis education often relies on passive lectures and individual case assessments. Team-based learning (TBL) offers an interactive alternative, but implementation challenges can exist. The 'Case of the Week (COW)' method presents a potentially modified TBL approach for oral diagnosis education.

Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation.

Alzheimer's disease (AD) is primarily caused by oxidative stress, hyperphosphorylated τ-protein aggregation, and amyloid-β deposition. Changes in dopaminergic and serotoninergic neurotransmitter pathways are linked to certain symptoms of AD. Derivatives of bicyclic and tricyclic cyclohepta[b]thiophene were developed to identify new potential candidates as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors for the treatment of AD.

Risk of swallowing disorders in patients with chronic rhinosinusitis and nasal polyposis in comparison to healthy controls: a Survey of 50 cases.

Purpose: To investigate the risk of swallowing disorders and the frequency and intensity of vocal tract symptoms in patients with chronic rhinosinusitis and nasal polyposis (CRSwNP).

Methods: Adult patients diagnosed with CRSwNP presenting to the rhinology clinic of a tertiary referral center between March 2023 and March 2024, were recruited. Patients with acute or recent history of respiratory tract infections, tonsillitis, pharyngitis or otitis, were excluded.

Incidental finding of hepatic pseudolesion from aberrant right gastric vein in a breast cancer patient.

Aberrant right gastric veins (ARGV) represent rare anatomical variations that can result in hepatic pseudolesions, mimicking malignancies due to their atypical drainage directly into the liver parenchyma. This case highlights a 44-year-old woman initially presenting with a breast mass incidentally found to have an ARGV-related pseudolesion in hepatic segment IVa. ARGV is clinically significant as it can alter hepatic blood flow dynamics, leading to hyperdense or hypodense regions on imaging.

Deferasirox and Ciprofloxacin: Potential Ternary Complex Formation With Ferric Iron, Pharmacodynamic, and Pharmacokinetic Interactions.

The main aim of this work was to assess the potential formation of ternary chelate complexes, involving deferasirox (DFX), ciprofloxacin (CP), and ferric iron. The coadministration of CP along with DFX might modulate its efficacy, so it is important that it be investigated. A ternary complex involving DFX, CP, and iron (DFX-CP-Fe) was prepared and characterized.