Alkaptonuria is a rare inherited disease resulting from a genetic variant leading to homogentisic acid accumulation in body tissues, causing a broad spectrum of symptoms. Our case involves a Caucasian male diagnosed in his 70s, who shares a constellation of symptoms and the diagnosis with his monozygotic twin brother. The symptoms include early-onset arthropathy, tendinopathy, osteopenia, discolouration of the auricular regions and fingers, scleral discolouration, secondary glaucoma, proteinuria, calcification of the mitral valve and black urethral and prostate stones.
View Article and Find Full Text PDFGundersen, AH, van den Tillaar, R, Falch, HN, Fredriksen, AB, and Larsen, S. A biomechanical comparison between conventional, sumo, and hex-bar deadlifts among resistance trained women. J Strength Cond Res XX(X): 000-000, 2024-The deadlift is a multijoint exercise frequently used to strengthen the lower extremities and spinal erectors.
View Article and Find Full Text PDFIntroduction: In the current digital age, the proliferation of misinformation presents a formidable challenge to a democratic society. False narratives surrounding vaccination efforts pose a significant public health risk. Understanding the role of cognitive biases in susceptibility to misinformation is crucial in addressing this challenge.
View Article and Find Full Text PDFGiven the profound societal impact of conspiracy theories, probing the psychological factors associated with their spread is paramount. Most research lacks large-scale behavioral outcomes, leaving factors related to actual online support for conspiracy theories uncertain. We bridge this gap by combining the psychological self-reports of 2506 Twitter (currently X) users with machine-learning classification of whether the textual data from their 7.
View Article and Find Full Text PDFWhile polyphenol consumption is often associated with an increased abundance of beneficial microbes and decreased opportunistic pathogens, these relationships are not completely described for polyphenols consumed via habitual diet, including culinary herb and spice consumption. This analysis of the International Cohort on Lifestyle Determinants of Health (INCLD Health) cohort uses a dietary questionnaire and 16s microbiome data to examine relationships between habitual polyphenol consumption and gut microbiota in healthy adults (n = 96). In this exploratory analysis, microbial taxa, but not diversity measures, differed by levels of dietary polyphenol consumption.
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