Publications by authors named "A L Fracanzani"

Article Synopsis
  • The study investigates the use of Artificial Intelligence (AI) to assess liver fibrosis in patients with Metabolic-Associated Steatotic Hepatitis (MASH) more accurately than traditional methods.
  • Out of 60 patients, biopsies were analyzed using AI technology to measure features like collagen area and entropy, revealing significant differences across fibrosis stages and treatment responses.
  • Results showed that AI could identify changes in fibrosis in 76% of cases post-treatment, suggesting it offers a more reliable way to evaluate disease progression and treatment efficacy.
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Article Synopsis
  • Diabetes mellitus (DM) has significant impacts on kidney and liver functions, leading to conditions like diabetic kidney disease (DKD) and metabolic dysfunction-associated steatotic liver disease (MASLD).
  • Management strategies for DKD include lifestyle changes and medications focusing on blood pressure and blood sugar control, while lifestyle modifications like weight loss and a Mediterranean diet are essential for MASLD.
  • There's a critical need for screening and tailored care for patients with DM and liver issues, especially in unique populations such as those on hemodialysis or kidney transplant recipients, highlighting the importance of a multidisciplinary approach.
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Introduction: Hepatocellular carcinoma (HCC) represents a major global health concern, characterized by evolving etiological patterns and a range of treatment options. Among various prognostic factors, sarcopenia, characterized by loss of skeletal muscle mass, strength, and function, has emerged as a pivotal contributor to HCC outcomes. Focusing on liver transplantation, surgical resection, locoregional treatments, and systemic therapies, this review aims to analyze the impact of sarcopenia on HCC treatment outcomes, shedding light on an underexplored subject in the pursuit of more personalized management.

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A systemic inflammatory response occurs during SARS-CoV2 infection and is associated with hypercoagulability and thrombotic events. From March 2020 in our hospital different dosages of low-molecular weight heparin (LMWH) were introduced according to the level of patient care intensity. Because bleeding episodes occurred in hospitalized COVID-19 patients on heparin, the dosage of LMWH at the end of first wave was tailored on the severity of COVID-19.

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Objectives: Although respiratory failure is the most common feature in coronavirus disease 2019 (COVID-19), abdominal organ involvement is likewise frequently observed. To investigate visceral and thoracic circulation and abdominal organ damage in COVID-19 patients.

Materials And Methods: A monocentric observational study was carried on.

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