Publications by authors named "A L Cabral"

Since prophages can play a multifaceted role in bacterial evolution, this study aims to characterize the virome of Rummeliibacillus stabekisii, a bacterium isolated from different environments, including Antarctic soil and NASA spacecraft floors. From the analyses, it was found that the Antarctic strain, PP9, had the largest number of prophages, including intact ones, indicating potential benefits for survival in adverse conditions. In contrast, other strains harbored predominantly degenerate prophages, suggesting a dynamic process of gene gain and loss during evolution.

View Article and Find Full Text PDF
Article Synopsis
  • The introduction of the 10-valent pneumococcal conjugate vaccine (PCV10) in Brazil has significantly decreased the prevalence of vaccine serotype-related invasive pneumococcal disease (IPD) in children, but non-vaccine serotypes, particularly 19A, have become more prominent.
  • The study analyzed 32 serotype 19A isolates from a variety of patients, finding that the majority of these isolates came from children and displayed high levels of non-susceptibility to commonly used antibiotics.
  • A significant number of the isolates were multidrug resistant, with a notable shift in genetic lineages, indicating evolving resistance patterns following the introduction of PCV10.
View Article and Find Full Text PDF

Background: The occurrence of strikes in the health sector has been an increasing concern around the world, given their negative impact on the provision of services and care to patients. The Mozambican doctors' strike in 2013 2013 is considered by many to be the largest of a kind in the country's history, and marked the changes which are still a matter of debate. The aim of this study is to understand the causes, strategies and perceived impact of this strike from the perspective of the main actors involved, taking a look back at everything that happened, including the backstage and tense moments during the negotiations.

View Article and Find Full Text PDF
Article Synopsis
  • The successful production of industrial natural products relies on strong microbial systems and reliable genetic tools to express target genes effectively.
  • The study combines the σlac and tet expression systems into one plasmid to evaluate their effectiveness in producing fluorescent reporters and terpenoids like lycopene and β-carotene in various bacteria.
  • Improvements in the expression systems, particularly by adding toehold switches for better control, enhance the production of biosynthetic intermediates, showing potential for advanced genetic tool applications.
View Article and Find Full Text PDF

Timor‑Leste is a lower‑middle‑income country in Southeast Asia. To control the significant local threat from infectious diseases, it is imperative to strengthen the knowledge and practice capabilities of the primary care workforce. We report and reflect on the development and delivery of a national training programme in infectious diseases called the Advancing Surveillance and Training to Enhance Recognition of Infectious Diseases (ASTEROID) programme, developed by the medical non‑governmental organisation (NGO) Maluk Timor and other Timorese stakeholders.

View Article and Find Full Text PDF