Publications by authors named "A L C E Silva"
Background: Pedal acceleration time (PAT) is a novel indicator of peripheral arterial disease in the lower limbs. Elevated PAT values are associated with worse limb ischemia. Arterial stiffness indexes are another class of indicators recently studied in patients with chronic limb-threatening ischemia (CLTI).
View Article and Find Full Text PDFMicroalgae hold significant potential for producing value-added bioproducts in pharmaceutical, cosmetic, food, and biofuel industries, with a global market value estimated at US$ 11.8 billion in 2023. Innovations in culturing systems, such as electric stimulation, aim to enhance growth performance, as it can improve cellular processes, including nutrient uptake and lipid accumulation.
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- The study aimed to explore the relationship between antisperm antibodies (ASA) and male fertility, highlighting contradictory reports on the topic.
- The research examined 2,727 men, categorizing them based on ASA presence and analyzing its effect on semen quality and reproductive health.
- Results showed that men with higher ASA levels had increased semen agglutination and leukocytes, indicating potential fertility issues, while smoking was linked to a higher likelihood of having pathological ASA levels.
Effect of 70 Gy tumor therapeutic radiation applied intermittently or directly on microcosm biofilm composition and dental hard tissues and its potential to cause dental caries.
J Dent
March 2025
Objectives: This study compared total (70 Gy, one session) and intermittent (35 sessions of 2 Gy) tumor radiation protocols on tooth morphology (n=5) using Scanning Electron Microscopy-Energy Dispersive X-ray (SEM-EDX) and on microcosm biofilm microbiota (n=12) through colony-forming unit (CFU) counts for Candida spp., total microorganisms, Streptococcus mutans, and total lactobacillus. It also assessed "radiation caries" development via Transverse Microradiography (TMR, n=12).
View Article and Find Full Text PDFThe crosstalk between tumour cells and microenvironment components in pituitary neuroendocrine tumours (PitNETs), including chemokines, may impact tumour behaviour and clinical outcomes. CCL2 was previously identified as a key chemokine in PitNETs, but its role remains unknown. We aimed to study the role of CCL2 in defining the phenotype and clinical outcomes of PitNETs, and in regulating macrophage chemotaxis, epithelial-to-mesenchymal transition (EMT) and angiogenesis.
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