Seatizen Atlas: a collaborative dataset of underwater and aerial marine imagery.

Citizen Science initiatives have a worldwide impact on environmental research by providing data at a global scale and high resolution. Mapping marine biodiversity remains a key challenge to which citizen initiatives can contribute. Here we describe a dataset made of both underwater and aerial imagery collected in shallow tropical coastal areas by using various low cost platforms operated either by citizens or researchers.

Nuclear Focal Adhesion Kinase Protects against Cisplatin Stress in Ovarian Carcinoma.

FAK inhibitors are in combinatorial clinical testing with agents that prevent Ras-Raf-MAPK pathway activation in various cancers. This study suggests that nuclear FAK limits ERK/MAPK activation in supporting HGSOC cell survival to cisplatin stress. Overall, it is likely that targets of FAK-mediated survival signaling may be tumor type- and context-dependent.

Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice.

Unlabelled: Focal adhesion kinase (FAK) functions as a signaling and scaffolding protein within endothelial cells (ECs) impacting blood vessel function and tumor growth. Interpretations of EC FAK-null phenotypes are complicated by related PYK2 (protein tyrosine kinase 2) expression, and to test this, we created PYK2 FAK mice with tamoxifen-inducible EC-specific Cre recombinase expression. At 11 weeks of age, EC FAK inactivation resulted in increased heart and lung mass and vascular leakage only on a PYK2 background.

Effects of Methyl Substitution on the Ultrafast Internal Conversion of Benzene.

The effects of methyl substitution on the ultrafast internal conversion from the S(B, ππ*) state to the S state of benzene were studied using ultrafast extreme-ultraviolet photoelectron spectroscopy and electronic structure calculations. The quantum yield of the internal conversion to the S state reached ∼0.69 in benzene, while lower values of 0.