Functional genomics implicates ebony in the black pupae phenotype of tephritid fruit flies.

The remarkable diversity of insect pigmentation offers a captivating avenue for studying evolution and genetics. In tephritids, understanding the molecular basis of mutant traits is also crucial for applied entomology, enabling the creation of genetic sexing strains through genome editing, thus facilitating sex-sorting before sterile insect releases. Here, we present evidence from classical and modern genetics showing that the black pupae (bp) phenotype in the GUA10 strain of Anastrepha ludens is caused by a large deletion at the ebony locus, removing the gene's entire coding region.

Clinical simulation training for first responders in pediatric emergencies with family interaction: a scoping review.

Objective: To map studies on clinical simulation training directed at first responders during pediatric emergencies, focusing on interaction with families.

Methods: A scoping review based on the guidelines of the JBI Manual for Evidence Syntheses and reported according to the PRISMA-ScR checklist, covering eight databases and gray literature, without time or language restrictions.

Results: The ten selected studies indicated that most publications were from the United States.

Cecal microbial composition and serum concentration of short-chain fatty acids in laying hens fed different fiber sources.

The intestinal microbiota is widely recognized as an integral factor in host health, metabolism, and immunity. In this study, the impact of dietary fiber sources on the intestinal microbiota and the production of short-chain fatty acids (SCFAs) was evaluated in Lohmann White laying hens. The hens were divided into four treatment groups: a control diet without fiber, a diet with wheat bran (mixed fibers), a diet with insoluble fiber (cellulose), and a diet with soluble fiber (pectin), with six replicates of four hens each.

Time to standardize educational competencies on EBP: the benefits of a common core framework.

Principles, theories, and models of education for health professionals have not evolved in parallel with advanced requirements for evidence-based practice (EBP). We propose that groups such as JBI, with a global network of clinical and academic centers, are well placed to reignite the debate and advance evidence-based curriculum development. This can be achieved by operationalizing the JBI Model for Evidence-Based Healthcare within the Sicily statement's pedagogical framework.

Oral hygiene of stroke patients in a stroke unit: a best practice implementation project.

Introduction: People with stroke are at risk of poor oral hygiene caused by neurological deficits, which can be motor, sensory, or cognitive. Good oral hygiene has been shown to reduce adverse events and improve the patient's quality of life. Although nurses recognize the benefits of oral hygiene, evidence shows that this area of care is frequently overlooked.