Publications by authors named "A Kushwah"

Cauliflower is an important winter crop grown in India, its curds are rich in nutritional profile, containing valuable minerals and vitamins. However, cauliflower harvesting is mainly accomplished by hands, which is time-consuming and requires a high labour force. On the other hand, most developed cauliflower harvesters are once over or single pass type, which harvests all plants irrespective of their maturity.

View Article and Find Full Text PDF
Article Synopsis
  • * PARP inhibitors (PARPi) are emerging as a treatment for mCRPC patients with specific genetic alterations, functioning by trapping PARP to increase DNA damage and induce cell death; however, their effectiveness typically wanes after 3-4 months due to the development of resistance.
  • * Resistance mechanisms to PARPi include mutations in DNA repair genes and pathways that restore DNA repair capabilities; strategies to overcome this resistance involve combining PARPi with other treatments or targeting different signaling pathways.
View Article and Find Full Text PDF

Fall armyworm (FAW), (J.E. Smith), a threat to maize production systems, is a polyphagous pest of global significance.

View Article and Find Full Text PDF

Ulcerative colitis (UC) is a prominent category of disease that is associated with bowel inflammation, it can occur at any period of life and is prevalently rising on a global scale. Dextran sulfate sodium (DSS) has been extensively used to develop colitis due to its ability to mimic human UC, providing consistent and reproducible inflammation, ulceration, and disruption of the epithelial barrier in the colon. Chronic inflammation in the gut can lead to alterations in the gut-liver axis, potentially impacting liver function over time, while direct evidence linking diversion colitis to liver damage is limited.

View Article and Find Full Text PDF

Background: Non-communicable diseases are chronic systemic inflammation in humans that occurs because of enhanced inflammatory mediators of the arachidonic acid cascade. We aimed to explore whether the lead chalcone compounds could exhibit anti-inflammatory activity via dual blockage of COX-2/5-LOX enzymes and their regulatory mechanism.

Methods: RAW 264.

View Article and Find Full Text PDF