Publications by authors named "A Kusaka"
Cine-magnetic resonance imaging (MRI) has been used to track respiratory-induced motion of the liver and tumor and assist in the accurate delineation of tumor volume. Recent developments in compressed sensitivity encoding (SENSE; CS) have accelerated temporal resolution while maintaining contrast resolution. This study aimed to develop and assess hepatobiliary phase (HBP) cine-MRI scans using CS.
View Article and Find Full Text PDFThe heat sensitivity of reproduction is a critical determinant of population persistence under climate change. However, the heat sensitivity of gametes has been much less studied relative to that of adults. We developed a method to measure the heat tolerance limits of lizard sperm cells, and used the method to test several aspects of sperm cell thermal biology in the brown anole lizard (Anolis sagrei).
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- Liquid biopsy (LB) is a minimally invasive method for analyzing tumor-derived materials, and this study explores the potential of bile as a superior source of cell-free DNA (cfDNA) compared to plasma for detecting mutations in biliary tract cancers.
- The research involved collecting cfDNA from the bile of 24 cancer cases, including various types of biliary tract cancers, and applying a multigene panel to identify cancer driver mutations.
- Results indicated that bile yielded a higher detection rate of cancer driver mutations, with 54% of bile samples testing positive compared to just 17% of plasma samples, highlighting bile's effectiveness for liquid biopsy analysis.