Cognitive behavioral therapy (CBT) is effective in treating adolescent depressive symptoms but with variable treatment response. Heterogeneity in treatment outcome may be due in part to individual differences in cognitive and emotional processes in depressed adolescents, and there is a need to identify biomarkers associated with symptoms and treatment outcomes. There has been growing interest in leveraging electroencephalography (EEG) data to examine correspondence between multiple frequency bands, and delta-beta coupling in particular is thought to underlie emotion regulation and offers a promising biomarker in adolescent depression.
View Article and Find Full Text PDFPregnancy is a period of profound biological transformation. However, we know remarkably little about pregnancy-related brain changes. To address this gap, we chart longitudinal changes in brain structure during pregnancy and explore potential mechanisms driving these changes.
View Article and Find Full Text PDFPregnancy is a period of profound biological transformation. However, we know remarkably little about pregnancy-related brain changes. To address this gap, we chart longitudinal changes in brain structure during pregnancy and explore potential mechanisms driving these changes.
View Article and Find Full Text PDFMore work is needed to establish the validity of the Alternative Model of Personality Disorders (AMPD) in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Acceptance of the AMPD as the primary model of personality disorder requires identifying neurocognitive validators of AMPD-defined personality functioning and demonstrating superiority of the AMPD over the traditional categorical model of personality disorder. It is also important to establish the utility of the AMPD in a developmental context given evidence that personality disorder emerges in adolescence.
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