Publications by authors named "A Kudoh"

Introduction: Hybrid total laparoscopic hysterectomy combines conventional laparoscopic surgery and robot-assisted devices: the camera and assistant forceps are operated by a robotic device, whereas the surgeon performs laparoscopic procedures, enabling surgery with a completely fixed field of view and significantly reducing errors in forceps grasping and needle misalignment. Here, we examined whether using two arms of the Hugo™ robot-assisted surgery system, one for the camera and one for the assistant, would improve surgical accuracy compared with conventional total laparoscopic hysterectomy.

Materials And Surgical Technique: The surgical system reduced surgeon errors in grasping the forceps during training and stabilized forceps operation.

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Few studies have compared the efficacy of robot-assisted, laparoscopic, and open surgeries for endometrial cancer. When considering the position of robotic surgery in Japan, it was necessary to determine whether it was effective or not. We aimed to compare the efficacy and safety of these three types of surgeries for early-stage endometrial cancer.

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Article Synopsis
  • Olaparib and niraparib, PARP inhibitors used in ovarian cancer treatment, are effective but cause high rates of nausea and vomiting in patients, with no established antiemetic guidelines.
  • A study involving 134 patients aimed to monitor the incidence of nausea and vomiting over 21 days, finding that only 21.7% received preventive antiemetic therapy.
  • The overall vomiting incidence was 16.3%, with lower rates for niraparib (10.3%) compared to olaparib (18.6%), suggesting they pose a low risk for emesis and may not require routine prophylactic antiemetics.
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In autosomal dominant polycystic kidney disease (ADPKD), renal cyst lesions predominantly arise from collecting ducts (CDs). However, relevant CD cyst models using human cells are lacking. Although previous reports have generated in vitro renal tubule cyst models from human induced pluripotent stem cells (hiPSCs), therapeutic drug candidates for ADPKD have not been identified.

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Malignant pericardial effusion is an uncommon metastatic manifestation of ovarian carcinoma. Few cases of ovarian serous carcinoma have been previously reported. Ovarian clear cell carcinoma is the second most common histologic subtype in East Asian countries and is a relatively rare in Western countries.

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